Welcome to the DEBtox information site
Welcome to the DEBtox information page, the
site for people that want to make sense of ecotoxicity data.
This site contains information on mechanistic models for the
analysis of stressor effects on the life-history traits of
individual organisms (and from there to higher and lower
levels of biological organisation). Specifically, this site
is about models based on animal energy budgets (DEBtox and DEBkiss) and survival models
from the GUTS framework.
This website constitutes a node in the international DEBnet
network, together with the associated site of DEBtox Research.
The mission of DEBtox.info is to simplify biology to
get to the essence of what toxicants (and other stresses)
are actually doing to organisms. Simplification is necessary
if we need to gain understanding. Furthermore, we cannot
expect to test even a small fraction of all possible
(combinations of) toxicants, species and environmental
conditions. Once we get to the essence, it is possible to
make educated predictions of toxicant effects for untested
chemicals, untested species, and under untested conditions.
Here, you can find information, lists of relevant
publications, (links to) free e-books, and freely
downloadable Matlab packages to analyse your data. Use the
major categories on the top left of the screen to navigate
through this site; the corresponding sub-categories will
appear right next to it in the submenu.
The free and open-source software
openGUTS is now available for download!
It is available as a standalone Windows executable
or as Matlab package. It supports the use of GUTS for regulatory
purposes, but will also prove useful for scientific
studies. The dedicated website http://openguts.info/
provides more information.
A calculation error was spotted in openGUTS,
which may affect IT calibrations/predictions
for specific types of exposure scenarios.
The Matlab version has been updated to v1.1
to repair this. For more information, see
users of BYOM versions before v. 4.3, see the notes
and warnings on the BYOM page
(bottom of page). If
you are working with BYOM, and would like to be
notified immediately in case of errors, new
versions, etc., email me
and I will include you in a mailing list. I may also
use this mailing list for other important
developments such as new (versions) of the e-books,
and new papers. This saves you the hassle of
checking this website every week ;-).
Upcoming courses and events
- Dedicated 2-day GUTS courses, geared towards
professionals in risk assessment of pesticides.
Wageningen, the Netherlands, dates to be announced. More information.
- In August 2021, we will again organise our
much-praised summer school "Dynamic modelling of toxic
effects" in Denmark. Registration is open, and will
close on 31 May 2020 (or when we reach the maximum
number of participants). More information on the course page. Download 2020 flyer.
NOTE: due to the COVID-19
situation, the 2020 course has been cancelled.
- Roman Ashauer and myself gave an on-line short course
on openGUTS at the
2020 SETAC SciCon. This course is now available for
everyone via Leanpub: https://leanpub.com/c/openguts.
Although you don't get the interaction with the
instructors, this is still a nice way to educate
yourself in quarantine.
Job opportunities for modellers
- Nothing at the moment (that I know of).
Older news over here.
- 29 May 2020: update for BYOM to version 5.0. This is a
major update, with much new functionality (incl. the
parameter-space explorer from openGUTS). See the BYOM page. Also an update
of the GUTS and DEBtox2019 packages to make use of the
- 11 Dec. 2019: new paper presenting an updated
simplified DEB model for ecotoxicology (based on
DEBkiss, compound parameters). See https://doi.org/10.1016/j.ecolmodel.2019.108904.
- 18 Sept. 2019: the GUTS course planned for October
2019 has been cancelled due to insufficient
- 2 Sept. 2019: update for BYOM and a new DEBtox2019
package (replacing DEBkiss-tox). See
the BYOM page.