Welcome to the DEBtox information site
Welcome to the DEBtox information page, the
site for people that want to make sense of ecotoxicity data.
This site contains information on mechanistic models for the
analysis of stressor effects on the life-history traits of
individual organisms (and from there to higher and lower
levels of biological organisation). Specifically, this site
is about models based on animal energy budgets (DEBtox and DEBkiss) and survival models
from the GUTS framework.
This website constitues a node in the international DEBnet
network, together with the associated site of DEBtox Research.
The mission of DEBtox.info is to simplify biology to
get to the essence of what toxicants (and other stresses)
are actually doing to organisms. Simplification is necessary
if we need to gain understanding. Furthermore, we cannot
expect to test even a small fraction of all possible
(combinations of) toxicants, species and environmental
conditions. Once we get to the essence, it is possible to
make educated predictions of toxicant effects for untested
chemicals, untested species, and under untested conditions.
Here, you can find information, lists of relevant
publications, (links to) free e-books, and freely
downloadable Matlab packages to analyse your data. Use the
major categories on the top left of the screen to navigate
through this site; the corresponding sub-categories will
appear right next to it in the submenu.
Upcoming courses and events
- For August 2018, we are planning to organise a new
round of the TKTD modelling summer course DynModTox in Denmark.
- For 2019, a new round of the DEB telecourse is planned,
and also a classroom part followed by the international
DEB symposium. This time, the location will be Brest,
Older news over here.
- 24 July 2017: Update of the "Making sense of chemical
stress" e-book. Improved
readability and update with new developments.
- 24 June 2017: Sandrine Charles wrote an excellent
review of my e-book in IEAM. http://dx.doi.org/10.1002/ieam.1931
- 14 June 2017: New paper from the EnergyBar
project: Jager T et al. Dynamic links between
lipid storage, toxicokinetics and mortality in a marine
copepod exposed to dimethylnaphthalene. Accepted in
Environ Sci Technol http://dx.doi.org/10.1021/acs.est.7b02212
- 12 May 2017: Spotted a small error in BYOM when
calculating the intervals on LC50s with the
likelihood-region method. This is corrected in a small update to version 4.01.
- 27-28 April 2017: Release of BYOM 4.0 on the BYOM page. This is a major
update, with many new features, but old scripts and
packages will not work anymore! All packages have been
updated; the two GUTS packages have been combined, and
some have been renamed for clarity. Plus, a new package
has been added to fit classical dose-response curves.
- 16 January 2017: A comprehensive review on DEB theory
by Marko Jusup and co-workers has just appeared on-line
of Life Reviews. The review is accompanied by a
number of commentaries.
- 29 November 2016: New paper from the EnergyBar
project: Jager T et al. (2017). Modelling the
dynamics of growth, development and lipid storage in the
marine copepod Calanus finmarchicus. Marine
Biology 164:1. DOI
10.1007/s00227-016-3030-8 (Open Access!)
- October 2016: The book "Marine Ecotoxicology: current
Knowledge and Future Issues" has just come out. I wrote
a chapter "Dynamic modelling for uptake and effects of
chemicals" in there. The book can obtained from Elsevier
or your favourite bookstore, or via ScienceDirect.
The support page for my chapter can be found over here.