DEBtox information
Making sense of ecotoxicity test results



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Welcome to the DEBtox information site


Welcome to the DEBtox information page, the site for people that want to make sense of ecotoxicity data. This site contains information on mechanistic models for the analysis of stressor effects on the life-history traits of individual organisms (and from there to higher and lower levels of biological organisation). Specifically, this site is about models based on animal energy budgets (DEBtox and DEBkiss) and survival models from the GUTS framework.

This website constitutes a node in the international DEBnet network, together with the associated site of DEBtox Research.

The mission of DEBtox.info  is to simplify biology to get to the essence of what toxicants (and other stresses) are actually doing to organisms. Simplification is necessary if we need to gain understanding. Furthermore, we cannot expect to test even a small fraction of all possible (combinations of) toxicants, species and environmental conditions. Once we get to the essence, it is possible to make educated predictions of toxicant effects for untested chemicals, untested species, and under untested conditions.

Here, you can find information, lists of relevant publications, (links to) free e-books, and freely downloadable Matlab packages to analyse your data. Use the major categories on the top left of the screen to navigate through this site; the corresponding sub-categories will appear right next to it in the submenu.

BREAKING NEWS!


The free and open-source software openGUTS is now available for download! It is available as a standalone Windows executable or as Matlab package. It supports the use of GUTS for regulatory purposes, but will also prove useful for scientific studies. The dedicated website http://openguts.info/ provides more information.

WARNING! A calculation error was spotted in openGUTS, which may affect IT calibrations/predictions for specific types of exposure scenarios. The Matlab version has been updated to v1.1 to repair this. For more information, see the openGUTS website.

WARNING! For users of BYOM versions before v. 4.3, see the notes and warnings on the BYOM page (bottom of page).
If you are working with BYOM, and would like to be notified immediately in case of errors, new versions, etc., email me and I will include you in a mailing list. I may also use this mailing list for other important developments such as new (versions) of the e-books, and new papers. This saves you the hassle of checking this website every week ;-).




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Upcoming courses and events


  • Dedicated 2-day GUTS courses, geared towards professionals in risk assessment of pesticides. Wageningen, the Netherlands, dates to be announced. More information.
  • In August 2021, we will again organise our much-praised summer school "Dynamic modelling of toxic effects" in Denmark. Registration is open, and will close on 31 May 2020 (or when we reach the maximum number of participants). More information on the course page. Download 2020 flyer. NOTE: due to the COVID-19 situation, the 2020 course has been cancelled.
  • Roman Ashauer and myself gave an on-line short course on openGUTS at the 2020 SETAC SciCon. This course is now available for everyone via Leanpub: https://leanpub.com/c/openguts. Although you don't get the interaction with the instructors, this is still a nice way to educate yourself in quarantine.

Job opportunities for modellers


  • Nothing at the moment (that I know of).

Latest news


  • 29 May 2020: update for BYOM to version 5.0. This is a major update, with much new functionality (incl. the parameter-space explorer from openGUTS). See the BYOM page. Also an update of the GUTS and DEBtox2019 packages to make use of the new functionality!
  • 11 Dec. 2019: new paper presenting an updated simplified DEB model for ecotoxicology (based on DEBkiss, compound parameters). See https://doi.org/10.1016/j.ecolmodel.2019.108904
  • 18 Sept. 2019: the GUTS course planned for October 2019 has been cancelled due to insufficient registrations.
  • 2 Sept. 2019: update for BYOM and a new DEBtox2019 package (replacing DEBkiss-tox). See the BYOM page.
Older news over here.


The DEBtox information site, www.debtox.info, since July 2011