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Courses / GUTS course

GUTS course

Starting 2019, we will be offering a regular 2-day course on: Using the General Unified Threshold Model of Survival (GUTS) in risk assessment of plant protection products. Download the flyer.

Target audience
This course aims at professionals interested in applying GUTS for the authorization of plant protection products (PPPs):
  • Consultants and business representatives working for industry and/or consulting agencies who apply GUTS for dossiers (evaluation, preparation and submission).
  • Scientists performing research on TKTD modelling with interest in GUTS applications in risk assessment.
  • Regulators working for admission authorities who evaluate dossiers containing GUTS applications or are in general interested in an improved link between exposure and effects.
Content & Result
The course focuses on the application of GUTS models for assessing the risk of PPP under time-variable exposure in aquatic systems. GUTS is the accepted toxicokinetic-toxicodynamic approach for the endpoint survival. The theory behind GUTS models will be introduced and course participants will learn how to use the latest implementation of the GUTS models in a user-friendly standalone software. Furthermore, they will practice assessing the results and learn how to interpret them. Hands-on exercises include model calibration and validation, and model predictions in consideration of the recommendations given by EFSA. Participants should at least hold a Bachelor degree or similar in natural sciences, and have some experience with the use of models, preferably in risk assessment.

Practical information

Location: Wageningen, The Netherlands (we will arrange a shuttle service from the train station Ede-Wageningen)
Dates: 16, 17 and 18 October 2019 (starting the afternoon of the 16th, ending after the morning of the 18th)
Course leader: Dr Andreas Focks (Wageningen Environmental Research)
Lecturers: Dr Roman Ashauer (Syngenta) and Dr Tjalling Jager (DEBtox research)
Maximum number of participants: 30

Course fee: €1950,- (no charge of VAT) and covers tuition, course materials, coffee/tea, lunches, 2 dinners.
Employees of an admission authority/university can apply for a reduced course fee of €1500,-.
Traveling and accommodation costs are not included.
A few places at a strongly reduced fee are available for PhD students, please contact the course leader for more information.

Registration: please register through this Google form: Registration and payment is handled by Wageningen UR.

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The TKTD summerschool was given from 2012-2016 and dealt with toxic effects on the energy budget using the DEBkiss simplification, and provided a more gentle introduction into DEB theory for animals. This summerschool is 'on hold' at the moment as we are thinking of different formats to provide courses on TKTD modelling. More information to follow in 2019.


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