Starting 2019, we will be offering
a regular 2-day course on: Using the General Unified
Threshold Model of Survival (GUTS) in risk assessment of
plant protection products.
This course aims at professionals interested in applying GUTS for the authorization of
plant protection products (PPPs):
Content & Result
- Consultants and business representatives working for
industry and/or consulting agencies who apply GUTS for
dossiers (evaluation, preparation and submission).
- Scientists performing research on TKTD modelling with
interest in GUTS applications in risk assessment.
- Regulators working for admission authorities who
evaluate dossiers containing GUTS applications or are in
general interested in an improved link between exposure
The course focuses on the application of GUTS models for
assessing the risk of PPP under time-variable exposure in
aquatic systems. GUTS is the accepted
toxicokinetic-toxicodynamic approach for the endpoint
survival. The theory behind GUTS models will be introduced
and course participants will learn how to use the latest
implementation of the GUTS models in a user-friendly standalone software.
Furthermore, they will practice assessing the results and
learn how to interpret them. Hands-on exercises include
model calibration and validation, and model predictions in
consideration of the recommendations
given by EFSA. Participants should at least hold a
Bachelor degree or similar in natural sciences, and have
some experience with the use of models, preferably in risk
Location: Wageningen, The
Dates: 16, 17 and 18 October 2019
Course leader: Dr
Andreas Focks (Wageningen Environmental Research)
Roman Ashauer (Syngenta) and Dr Tjalling Jager
Maximum number of participants: 30
Course fee: €1950,- (no charge of VAT) and covers
tuition, course materials, coffee/tea, lunches, 2 dinners.
Employees of an admission authority/university can apply for
a reduced course fee of €1500,-.
Traveling and accommodation costs are not included.
Registration: to be announced.
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animals. This summerschool is 'on hold' at the moment as we
are thinking of different formats to provide courses on TKTD
modelling. More information to follow in 2019.