Welcome to the DEBtox information site
Welcome to the DEBtox information page, the
site for people that want to make sense of ecotoxicity data.
This site contains information on mechanistic models for the
analysis of stressor effects on the life-history traits of
individual organisms (and from there to higher and lower
levels of biological organisation). Specifically, this site
is about models based on animal energy budgets (DEBtox and DEBkiss) and survival models
from the GUTS framework.
This website constitues a node in the international DEBnet
network, together with the associated site of DEBtox Research.
The mission of DEBtox.info is to simplify biology to
get to the essence of what toxicants (and other stresses)
are actually doing to organisms. Simplification is necessary
if we need to gain understanding. Furthermore, we cannot
expect to test even a small fraction of all possible
(combinations of) toxicants, species and environmental
conditions. Once we get to the essence, it is possible to
make educated predictions of toxicant effects for untested
chemicals, untested species, and under untested conditions.
Here, you can find information, lists of relevant
publications, (links to) free e-books, and freely
downloadable Matlab packages to analyse your data. Use the
major categories on the top left of the screen to navigate
through this site; the corresponding sub-categories will
appear right next to it in the submenu.
WARNING! For users of BYOM, see the notes and
warnings on the BYOM page.
Specifically pertinent: the likelihood-region method
yielded exaggerated confidence intervals on model
predictions (fixed in version 4.2), and the LPx
calculations (used with GUTS, to calculate
multiplication factors on concentration profiles) is
biassed when there is substantial background mortality
in the calibration data set (fixed in version 4.2b).
If you are working with
BYOM, and would like to be notified immediately in
case of errors, new versions, etc., email me and I will
include you in a mailing list. I may also use this
mailing list for other important developments such
as new (versions) of the e-books, and new papers.
This saves you the hassle of checking this website
every week ;-).
Upcoming courses and events
- We unfortunately had to cancel the 2018 round of the
TKTD modelling summer course DynModTox
in Denmark. we hope to have more information on the next
round, or somewhat different courses, in the near
- For 2019, a new round of the DEB telecourse is planned,
and also a classroom part (1-6 April), followed by
workshops (8-9 April), and the international DEB
symposium (10-12 April). This time, the location will be
Brest, France. More information is provided on the symposium
website, which will be filled with more
information in the course of 2018. Application to the
DEB2019 school is open and will close on January 21st,
- If you are a young environmental scientist, make sure
to check out the YES
meeting in Ghent, 5-10 February 2019. I will be
teaching a short course on DEBkiss there. Registration
deadline is 18 December 2018.
Job opportunities for modellers
- Nothing special that I know of.
Older news over here.
- 9 January 2019: new paper on automated high-throughput
measurements of body size (which could really facilitate
DEB(tox) application in the future). Open
access. Note that this is my 100th (co-)authored
- 8 December 2018: a new version of the GUTS e-book has
been released at Leanpub. Most
important change is in the statistical treatment. See
version log at the support
page for more details.
- 15 November 2018: a new version of the DEBkiss e-book
has been released at Leanpub.
- 7 September 2018: small update of BYOM to v. 4.2c and
updated GUTS package v. 2.3. More details on the BYOM page.
- 27 August 2018: the EFSA opinion on TKTD models is now
here. This opinion will be pivotal for the
application of GUTS and DEBtox in environmental risk
assessment (in particular for pesticides).