Welcome to the DEBtox information site
Welcome to the DEBtox information page, the
site for people that want to make sense of ecotoxicity data.
This site contains information on mechanistic models for the
analysis of stressor effects on the life-history traits of
individual organisms (and from there to higher and lower
levels of biological organisation). Specifically, this site
is about models based on animal energy budgets (DEBtox and DEBkiss) and survival models
from the GUTS framework.
This website constitues a node in the international DEBnet
network, together with the associated site of DEBtox Research.
The mission of DEBtox.info is to simplify biology to
get to the essence of what toxicants (and other stresses)
are actually doing to organisms. Simplification is necessary
if we need to gain understanding. Furthermore, we cannot
expect to test even a small fraction of all possible
(combinations of) toxicants, species and environmental
conditions. Once we get to the essence, it is possible to
make educated predictions of toxicant effects for untested
chemicals, untested species, and under untested conditions.
Here, you can find information, lists of relevant
publications, (links to) free e-books, and freely
downloadable Matlab packages to analyse your data. Use the
major categories on the top left of the screen to navigate
through this site; the corresponding sub-categories will
appear right next to it in the submenu.
WARNING! The 2018 course has been cancelled
due to personal circumstances. We are at the moment
reconsidering the course contents and format, and
will post more information here as soon as the plans
are more concrete.
On 18 January 2018, the
long-awaited GUTS e-book was released. More information on
the book's support page.
Upcoming courses and events
- We unfortunately had to cancel the 2018 round of the
TKTD modelling summer course DynModTox
in Denmark. we hope to have more information on the next
round, or somewhat different courses, in the near
- For 2019, a new round of the DEB telecourse is planned,
and also a classroom part followed by the international
DEB symposium. This time, the location will be Brest,
France. More information is provided on the symposium
website, which will be filled with more
information in the course of 2018.
Job opportunities for modellers
- Postdoc position on DEB/population modelling for
freshwater mussels in the US. Download
Older news over here.
- 28 June 2018: running simulations for GUTS, I am
getting confirmation that the likelihood-region method
(as implemented in BYOM) is yielding exaggerated
confidence intervals on model predictions. More
details on the BYOM page.
- In 2018/2019 we will be producing a user-friendly
software for GUTS. More
- 27 March 2018: new paper from the GUTS
project on evaluating the quality of
toxicokinetic-toxicodynamic models. IEAM. https://doi.org/10.1002/ieam.2026
- 26 March 2018: the 2018 round of the TKTD modelling
summer course DynModTox
has been cancelled.
- 1 February 2018: New versions of BYOM and the GUTS
package. See the BYOM page.
- 18 January 2018: The long-awaited GUTS e-book is
released in Version 1.0! More
- 1 November 2017: New paper from the GUTS
project: Physiological modes of action across
species and toxicants: the key to predictive
ecotoxicology. Environ. Sci.: Processes Impacts. Open