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Making sense of ecotoxicity test results



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Welcome to the DEBtox information site


Welcome to the DEBtox information page, the site for people that want to make sense of ecotoxicity data. This site contains information on mechanistic models for the analysis of stressor effects on the life-history traits of individual organisms (and from there to higher and lower levels of biological organisation). Specifically, this site is about models based on animal energy budgets (DEBtox and DEBkiss) and survival models from the GUTS framework.

This website constitues a node in the international DEBnet network, together with the associated site of DEBtox Research.

The mission of DEBtox.info  is to simplify biology to get to the essence of what toxicants (and other stresses) are actually doing to organisms. Simplification is necessary if we need to gain understanding. Furthermore, we cannot expect to test even a small fraction of all possible (combinations of) toxicants, species and environmental conditions. Once we get to the essence, it is possible to make educated predictions of toxicant effects for untested chemicals, untested species, and under untested conditions.

Here, you can find information, lists of relevant publications, (links to) free e-books, and freely downloadable Matlab packages to analyse your data. Use the major categories on the top left of the screen to navigate through this site; the corresponding sub-categories will appear right next to it in the submenu.

Special request


Roman Ashauer and myself are organising a ring test for GUTS software implementations, as part of our CEFIC-LRI project. We are currently inviting the 'owner/developers' of various implementations that we know of. If you have developed a GUTS implementation, and would like to join in, and have not been invited already, please contact me as soon as possible!



The
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The Duck of Vaucanson

Upcoming courses and events


  • In the first part of 2017, there will another round of the international DEB course, with a tele part (March-April at your own location) and a hands-on part (in Tromsø, Norway, 21-30 May). More information.
  • 31 May-2 June. Immediately after the DEB course, there will be the 5th International DEB Symposium, also in Tromsø (call for abstracts has opened). More information.
  • 10-13 July 2017. PREDITOX summer school in Lyon, France. The school aims at helping to improve skills in modelling (incl. TKTD modelling) and statistical inference for a better analysis of bioassays. More information: https://sites.google.com/view/preditox2017/home  

Job opportunities


  • The 2017 edition of the LabexMER post-doctoral program for young scientists is now opened. The aim of the program is to give creative young scientists the opportunity to develop their own research project in one of the LabexMER laboratories (France). Deadline for applications: April 15th, 2017. The Brest group of DEB modelers encourage applications dealing with the modelling of the effect of multiple stressors on marine organisms in support of lab experiments. More information.

Latest news


  • 15 February 2017: Added a Beta test version of BYOM 4.0 on the BYOM page. This is still under testing, but feel free to play with it. Also, I added some warnings for users of profiling and slice sampling with BYOM.
  • 16 January 2017: A comprehensive review on DEB theory by Marko Jusup and co-workers has just appeared on-line in Physics of Life Reviews. The review is accompanied by a number of commentaries.
  • 5 January 2017: New version of the BYOM platform available for download.
  • 1 January 2017: Our GUTS paper has just hit 100 citations in Web of Science! DOI 10.1021/es103092a.
  • 6 December 2016: New version of the DEBkiss book published. More information.
  • 29 November 2016: New paper from the EnergyBar project: Jager T et al. (2017). Modelling the dynamics of growth, development and lipid storage in the marine copepod Calanus finmarchicus. Marine Biology 164:1. DOI 10.1007/s00227-016-3030-8 (Open Access!)
  • October 2016: The book "Marine Ecotoxicology: current Knowledge and Future Issues" has just come out. I wrote a chapter "Dynamic modelling for uptake and effects of chemicals" in there. The book can obtained from Elsevier or your favourite bookstore, or via ScienceDirect. The support page for my chapter can be found over here.
Older news over here.


The DEBtox information site, www.debtox.info, since July 2011